Description

tert-Butyl Tosylate is a versatile and highly reactive alkylating agent and protecting group reagent widely used in organic synthesis. Its primary value lies in its ability to introduce the tert-butyl group under mild conditions, serving as a key intermediate for constructing complex molecules. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material industries.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing sterically hindered tert-butyl groups.
• Peptide Synthesis: Used as a protecting agent for carboxylic acids and other functional groups during solid-phase and solution-phase peptide synthesis.
• Agrochemical Production: Intermediate in the manufacture of herbicides, fungicides, and other crop protection agents requiring tert-butyl moieties.
• Material Science: Monomer or modifying agent in the production of specialty polymers, resins, and advanced organic materials.
• Organic Synthesis Reagent: Employed in alkylation reactions, esterifications, and as a precursor for generating tert-butyl carbocations.
• Laboratory Research: Standard reagent for method development and exploratory chemistry in academic and industrial R&D settings.

Basic Information

Product Name	tert-Butyl Tosylate
CAS No.	4664-57-7
Molecular Formula	C11H16O3S
Molecular Weight	228.31 g/mol
Synonyms	tert-Butyl p-toluenesulfonate; 4-Methylbenzenesulfonic acid tert-butyl ester; p-Toluenesulfonic acid tert-butyl ester; t-Butyl tosylate; TBTS; tert-Butyl 4-methylbenzenesulfonate; 1,1-Dimethylethyl 4-methylbenzenesulfonate
EINECS	225-124-8

Quality Control

Our tert-Butyl Tosylate is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	34 - 38 °C
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.