Description

Toluene-4-Sulfonic Acid2-[4-(tert-Butyl-Dimethyl-Silanyloxy)-7A-Methyl-Octahydro-Inden-1-Yl]-Propyl Ester is a specialized organosilicon-protected intermediate of significant value in advanced organic synthesis. This compound matters for its role as a key building block in the synthesis of complex molecules, offering precise control over reaction pathways. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the production of novel active ingredients. Its unique structure facilitates challenging synthetic transformations where protecting group chemistry is critical.

Application

• Pharmaceutical Intermediate: Serves as a crucial protected synthon in the multi-step synthesis of novel drug candidates, particularly in steroid or terpenoid-related chemistry.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where its siloxy-protected group allows for selective functionalization.
• Advanced Material Research: Acts as a precursor in the development of specialty polymers or liquid crystals that require specific, sterically hindered molecular architectures.
• Academic & Process Chemistry: Employed in university and industrial R&D labs for methodological studies in total synthesis and protecting group strategy optimization.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for fine chemical manufacturers offering bespoke synthesis services for client-specific molecular targets.

Basic Information

Item	Details
Product Name	Toluene-4-Sulfonic Acid2-[4-(tert-Butyl-Dimethyl-Silanyloxy)-7A-Methyl-Octahydro-Inden-1-Yl]-Propyl Ester
CAS No.	100928-04-9
Molecular Formula	C28H48O4SSi
Molecular Weight	508.83 g/mol
Synonyms	p-Toluenesulfonic Acid 2-[4-[(1,1-Dimethylethyl)dimethylsilyl]oxy]-7a-methyloctahydro-1H-inden-1-yl]propyl Ester; 2-[4-(tert-Butyldimethylsilyloxy)-7a-methyloctahydroinden-1-yl]propyl Tosylate; TBDMS-protected Indanylpropyl Tosylate; (1R,4S,7aS)-4-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-7a-methyl-1-[(2-[(4-methylphenyl)sulfonyl]oxy]propyl]octahydro-1H-indene; Tosylate Ester of Siloxy-Indane Derivative
EINECS	Contact for details

Quality Control

Every batch of our Toluene-4-Sulfonic Acid Ester intermediate undergoes rigorous analytical testing to ensure identity, purity, and consistency. We employ advanced techniques including HPLC, GC, NMR, and mass spectrometry to verify specifications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.