Description

L-Aspartic Acid Bis-Allyl Ester p-Toluenesulfonate Salt is a specialized, high-purity chemical intermediate designed for advanced synthesis. This compound is critical for researchers and manufacturers requiring a protected aspartic acid derivative for the controlled construction of complex molecules. It is primarily utilized in the development of novel pharmaceuticals, peptide-based materials, and fine chemicals where precise molecular architecture is essential.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of peptide drugs, prodrugs, and active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis (SPPS) where the allyl ester protecting groups offer orthogonal deprotection strategies.
• Bioconjugation & Linker Chemistry: Serves as a precursor for creating cleavable linkers or functionalized scaffolds in bioconjugation and drug delivery system development.
• Polymer Science: Employed in the synthesis of functional polymers and dendrimers with tailored biocompatibility or degradation profiles.
• Research & Development: Essential for academic and industrial R&D in medicinal chemistry, chemical biology, and material science.
• Fine Chemical Synthesis: A versatile intermediate for creating chiral compounds and other high-value specialty chemicals.

Basic Information

Product Name	L-Aspartic Acid Bis-Allyl Ester p-Toluenesulfonate Salt
CAS No.	125229-60-9
Molecular Formula	C20H27NO8S
Molecular Weight	441.50 g/mol
Synonyms	L-Aspartic Acid β-Allyl Ester α-Allyl Ester p-Toluenesulfonate Salt; Aspartic Acid Bis(allyl ester) Tosylate Salt; H-Asp(OAll)-OAll · TosOH; (2S)-2-Amino-4-(allyloxy)-4-oxobutanoic acid 2-allyl ester 4-methylbenzenesulfonate; Bis-allyl L-aspartate p-toluenesulfonate; 125229-60-9; L-Aspartic acid diallyl ester tosylate
EINECS	Contact for details

Quality Control

Our L-Aspartic Acid Bis-Allyl Ester p-Toluenesulfonate Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, NMR for structural confirmation, and KF titration for moisture content. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.