Description

(R)-2-(Boc-Amino)-2-Phenylethyl 4-Methylbenzenesulfonate is a high-purity chiral building block and synthetic intermediate of significant value in advanced organic synthesis. Its core value lies in providing a protected amino alcohol functionality with a leaving group, enabling the stereoselective construction of complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for the development of active pharmaceutical ingredients (APIs) and novel chiral ligands.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of enantiomerically pure drugs, especially those targeting neurological and cardiovascular disorders.
• Peptidomimetics & Amino Acid Derivatives: Used in the preparation of non-natural amino acids and peptide analogs for drug discovery and biochemical research.
• Asymmetric Synthesis: Serves as a precursor for chiral auxiliaries, catalysts, and ligands used in stereocontrolled chemical transformations.
• Protecting Group Chemistry: The Boc (tert-butoxycarbonyl) group allows for orthogonal protection strategies in multi-step synthetic sequences.
• Chemical Biology Probes: Utilized in the development of labeled compounds and molecular probes for studying biological mechanisms.

Basic Information

Product Name	(R)-2-(Boc-Amino)-2-Phenylethyl 4-Methylbenzenesulfonate
CAS No.	126610-77-3
Molecular Formula	C20H25NO5S
Molecular Weight	391.48 g/mol
Synonyms	(R)-2-[(tert-Butoxycarbonyl)amino]-2-phenylethyl 4-methylbenzenesulfonate; (R)-N-Boc-2-amino-2-phenylethyl tosylate; (R)-2-(tert-Butoxycarbonylamino)-2-phenylethyl tosylate; (R)-Boc-Phenylglycinol Tosylate; (R)-BocNHCH(C6H5)CH2OTs; (R)-1-[[(1,1-Dimethylethoxy)carbonyl]amino]-1-phenyl-2-[(4-methylphenyl)sulfonyl]oxy]ethane; (R)-N-Boc-1-phenyl-2-tosyloxyethylamine
EINECS	Contact for details

Quality Control

Our (R)-2-(Boc-Amino)-2-Phenylethyl 4-Methylbenzenesulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a desiccated environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.