Description

6-o-Tosyl-D-Mannose is a key protected carbohydrate intermediate, specifically a tosylated derivative of D-mannose. This compound is essential for synthetic chemists as it provides a reactive site for further selective functionalization while protecting the sugar's hydroxyl group. It is primarily utilized in the research and development of complex oligosaccharides, glycoconjugates, and novel pharmaceutical agents. The high purity and consistent quality of this intermediate are critical for ensuring reproducibility in advanced organic synthesis and glycoscience applications.

Application

• Glycochemistry Research: A fundamental building block for the synthesis of complex oligosaccharides and glycans.
• Pharmaceutical Intermediates: Used in the development of glycosylated drugs, prodrugs, and diagnostic agents.
• Glycoconjugate Synthesis: Critical for creating glycoproteins, glycolipids, and other biologically active conjugates.
• Carbohydrate Chemistry: Serves as a versatile starting material for the preparation of various mannose derivatives and analogs.
• Chemical Biology Probes: Employed in the synthesis of labeled sugars for metabolic pathway studies and imaging.
• Enzyme Substrate Studies: Used to investigate the activity and inhibition of glycosyltransferases and other carbohydrate-processing enzymes.

Basic Information

Product Name	6-o-Tosyl-D-Mannose
CAS No.	105265-64-3
Molecular Formula	C13H18O8S
Molecular Weight	334.34 g/mol
Synonyms	D-Mannose, 6-(4-methylbenzenesulfonate); 6-O-(p-Tolylsulfonyl)-D-mannose; 6-O-Tosyl-D-mannopyranose; 6-O-(4-Methylphenylsulfonyl)-D-mannose; D-Mannose 6-tosylate; 6-Tosyl-D-mannose; Mannose 6-tosylate; p-Toluenesulfonic acid 6-D-mannopyranosyl ester
EINECS	Contact for details

Quality Control

Our 6-o-Tosyl-D-Mannose is manufactured under strict quality control protocols to ensure high chemical purity and batch-to-batch consistency, suitable for demanding research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemical production, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.