Description

(R)-2-Hydroxybutyl p-Tosylate,98+% is a high-purity chiral building block and tosylate ester of significant synthetic utility. This compound is valued for its role as a key intermediate in the stereoselective synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing chiral centers with defined (R)-configuration.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
• Asymmetric Synthesis: Used in nucleophilic substitution reactions (SN2) where the tosylate is an excellent leaving group, enabling the introduction of the (R)-2-hydroxybutyl moiety.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands or organocatalysts used in enantioselective transformations.
• Agrochemical Research: Employed in the development of chiral pesticides and herbicides where biological activity is stereospecific.
• Fine Chemical Synthesis: Used in custom and contract manufacturing for producing specialty chemicals with high enantiomeric purity.
• Academic Research: A valuable reagent for methodological studies in organic chemistry and stereochemistry education.

Basic Information

Product Name	(R)-2-Hydroxybutyl p-Tosylate,98+%
CAS No.	103745-07-9
Molecular Formula	C11H16O4S
Molecular Weight	244.31 g/mol
Synonyms	(R)-2-Hydroxybutyl 4-methylbenzenesulfonate; (R)-Butane-1,2-diol 1-tosylate; (R)-1-Tosyloxybutan-2-ol; p-Toluenesulfonic acid (R)-2-hydroxybutyl ester; (R)-2-Hydroxybutyl tosylate; (R)-1,2-Butanediol monotosylate; (R)-2-Butanol, 1-(4-methylbenzenesulfonate)
EINECS	Contact for details

Quality Control

Our (R)-2-Hydroxybutyl p-Tosylate,98+% is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is analyzed using advanced chromatographic (HPLC, GC) and spectroscopic (NMR) techniques. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profile is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.