Description

3-Fluoro-Benzamidine is a high-purity, fluorinated benzamidine derivative serving as a critical building block in advanced organic synthesis. Its primary value lies in its role as a versatile amidine precursor, enabling the introduction of the amidoxime functional group into complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, particularly for developing novel enzyme inhibitors, ligands, and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key synthon for the development of protease inhibitors, including trypsin-like serine protease inhibitors with potential therapeutic applications.
• Agrochemical Research: Used in the synthesis of novel herbicides and fungicides, leveraging the fluorine atom for enhanced bioactivity and environmental stability.
• Chemical Biology & Proteomics: Serves as a precursor for affinity chromatography ligands and activity-based probes to study enzyme function and protein interactions.
• Material Science: Building block for creating functionalized polymers and metal-organic frameworks (MOFs) with specific binding or catalytic properties.
• Organic Synthesis: Versatile reagent for constructing heterocyclic compounds, such as pyrimidines and triazines, through cyclization reactions.

Basic Information

Product Name	3-Fluoro-Benzamidine
CAS No.	69491-64-1
Molecular Formula	C7H7FN2
Molecular Weight	138.14 g/mol
Synonyms	3-Fluorobenzamidine; m-Fluorobenzamidine; Benzenecarboximidamide, 3-fluoro-; 3-Fluorobenzenecarboximidamide; 3-FBA; 3-Fluorophenylamidine; 3-Fluorobenzimidamide; (3-Fluorophenyl)methanimidamide
EINECS	Contact for details

Quality Control

Our 3-Fluoro-Benzamidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP starting material requirements. Specifications can be tailored to meet specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.