Description

2-Fluoro-4-Nitrobenzotrifluoride is a high-value fluorinated aromatic nitro compound that serves as a critical building block in advanced chemical synthesis. Its unique structure, featuring both a nitro and a trifluoromethyl group on a fluorinated benzene ring, makes it an indispensable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials, improving dielectric anisotropy and thermal stability.
• Functional Dye & Pigment Production: Employed in the manufacture of specialized dyes and pigments where the nitro and trifluoromethyl groups influence color fastness and solubility.
• Organic Synthesis & Cross-Coupling Reactions: Acts as a versatile substrate in palladium-catalyzed reactions (e.g., Suzuki, Buchwald-Hartwig) for constructing complex biaryl structures.
• Research & Development: Utilized in academic and industrial R&D labs for exploring new fluorination methodologies and creating compound libraries for screening.

Basic Information

Product Name	2-Fluoro-4-Nitrobenzotrifluoride
CAS No.	69411-67-2
Molecular Formula	C7H3F4NO2
Molecular Weight	209.10 g/mol
Synonyms	1-Fluoro-2-nitro-4-(trifluoromethyl)benzene; 2-Fluoro-α,α,α-trifluoro-4-nitrotoluene; 4-Nitro-2-fluorobenzotrifluoride; 2-Fluoro-4-nitro-α,α,α-trifluorotoluene; Benzene, 1-fluoro-2-nitro-4-(trifluoromethyl)-; 2-Fluoro-4-nitrobenzylidene trifluoride; 4-Nitro-2-fluorobenzyl trifluoride
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-Nitrobenzotrifluoride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade intermediate synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in darkness.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Purity (GC)	≥97.0%
Melting Point	40°C - 44°C
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.