Description

14-Hydroxy Carminomycin is a key anthracycline derivative and a significant intermediate in the synthesis of advanced pharmaceutical compounds. Its value lies in its structural role as a precursor for developing potent chemotherapeutic agents, particularly in oncology research. This compound is essential for pharmaceutical R&D laboratories and manufacturers focused on producing innovative cancer therapeutics and studying anthracycline-based drug mechanisms.

Application

• Pharmaceutical Intermediate: Primary use as a critical building block in the synthesis of novel anthracycline chemotherapeutic drugs.
• Oncology Research: Serves as a reference standard and active pharmaceutical ingredient (API) intermediate in preclinical and clinical cancer research studies.
• Biochemical Research: Used in studies investigating the mechanism of action, structure-activity relationships (SAR), and DNA-intercalating properties of anthracyclines.
• Antibiotic Development: Acts as a precursor in the development of new anthracycline-class antibiotics with modified efficacy and reduced side-effect profiles.
• Academic & Contract Research: Utilized by universities and CROs (Contract Research Organizations) for chemical biology and medicinal chemistry projects.
• GMP Manufacturing: Supplied as a high-purity intermediate for cGMP (Current Good Manufacturing Practice) production of approved pharmaceutical products.

Basic Information

Product Name	14-Hydroxy Carminomycin
CAS No.	69401-50-9
Molecular Formula	C₂₆H₂₉NO₁₀
Molecular Weight	515.51 g/mol
Synonyms	14-Hydroxycarminomycin; 14-OH-Carminomycin; 7-Deoxy-14-hydroxydaunorubicin; 14-Hydroxy-13-dihydrocarminomycin; Carminomycin I 14-hydroxy derivative; (8S,10S)-8-Acetyl-10-[(2S,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,8,11-trihydroxy-1-methoxy-9,10-dihydro-7H-tetracene-5,12-dione
EINECS	Contact for details

Quality Control

Our 14-Hydroxy Carminomycin is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency, suitable for demanding research and GMP applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant ICH guidelines and can supply material that meets in-house specifications aligned with pharmaceutical intermediate standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	Red to orange-red powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single unknown impurity ≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.