Description

N1-[3-[[3-[(1-Phenylethyl)Amino]Propyl]Amino]Propyl]Bleomycinamide is a chemically modified derivative of the bleomycin family, a class of glycopeptide antibiotics known for their potent antitumor activity. This compound is of significant interest in pharmaceutical research and development due to its potential as a key intermediate or active pharmaceutical ingredient (API) in novel oncology therapeutics. It is primarily utilized by research institutions, pharmaceutical manufacturers, and biotechnology companies engaged in the synthesis and evaluation of next-generation chemotherapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel bleomycin-based anticancer drugs.
• Oncology Research: Used in biochemical and pharmacological studies to investigate mechanisms of action, DNA cleavage, and cytotoxicity against various cancer cell lines.
• API Development: Acts as a precursor or the active component in the formulation of experimental chemotherapeutic formulations.
• Bioconjugation Studies: Employed in research focused on attaching targeting moieties (like antibodies) to enhance drug specificity and reduce systemic toxicity.
• Mechanism of Action Probes: Utilized to study the structure-activity relationships (SAR) within the bleomycin family to design more effective or less toxic analogs.
• Standards and References: Provides a high-purity chemical standard for analytical method development, quality control, and regulatory submissions in drug development pipelines.

Basic Information

Product Name	N1-[3-[[3-[(1-Phenylethyl)Amino]Propyl]Amino]Propyl]Bleomycinamide
CAS No.	69235-65-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Bleomycinamide, N1-[3-[[3-[(1-phenylethyl)amino]propyl]amino]propyl]-; Bleomycin derivative; Phenylalanine bleomycin derivative; N1-(3-{3-[(1-Phenylethyl)amino]propylamino}propyl)bleomycinamide; (S)-N1-(3-((3-(1-Phenylethylamino)propyl)amino)propyl)bleomycinamide
EINECS	Contact for details

Quality Control

Our N1-[3-[[3-[(1-Phenylethyl)Amino]Propyl]Amino]Propyl]Bleomycinamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider conditions under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.