Description

N1-[3-[[3-(Dimethylamino)Propyl]Amino]Propyl]Bleomycinamide is a chemically modified derivative of the bleomycin family of glycopeptide antibiotics. This compound is of significant interest in pharmaceutical research and development, particularly for its potential as a targeted therapeutic agent or as a key intermediate in the synthesis of novel drug conjugates. It is primarily utilized by research institutions, pharmaceutical companies, and biotechnology firms engaged in oncology drug discovery and advanced medicinal chemistry.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of next-generation bleomycin-based anticancer agents and antibody-drug conjugates (ADCs).
• Oncology Research: Used in biochemical and pharmacological studies to investigate mechanisms of DNA cleavage and cytotoxicity for cancer therapy development.
• Drug Discovery: Employed as a model compound for structure-activity relationship (SAR) studies to optimize the efficacy and reduce the side effects of bleomycin analogues.
• Bioconjugation: The functionalized side chain allows for site-specific conjugation to targeting moieties like antibodies, peptides, or nanoparticles for targeted drug delivery systems.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation in pharmaceutical manufacturing.

Basic Information

Product Name	N1-[3-[[3-(Dimethylamino)Propyl]Amino]Propyl]Bleomycinamide
CAS No.	69235-61-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Bleomycinamide, N1-[3-[[3-(dimethylamino)propyl]amino]propyl]-; N1-(3-((3-(Dimethylamino)propyl)amino)propyl)bleomycinamide; Bleomycin derivative (69235-61-6); Modified Bleomycin A5; Bleomycinamide propylamine derivative
EINECS	Contact for details

Quality Control

Our N1-[3-[[3-(Dimethylamino)Propyl]Amino]Propyl]Bleomycinamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatographic purity assays and structural confirmation, to ensure it meets the stringent requirements for pharmaceutical research. A Certificate of Analysis (COA) detailing purity, identity, and related substances is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccants or an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	≤ 5.0% total
Water Content (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.