Description

N1-[3-[[3-[[2-(4-Chlorocyclohexyl)-1-Iminoethyl]Amino]Propyl]Methylamino]Propyl]Bleomycinamide is a chemically modified derivative of the bleomycin family, designed for enhanced research and development applications. This compound is of significant interest for its potential in creating novel conjugates and exploring structure-activity relationships in targeted therapeutic areas. It is primarily utilized by pharmaceutical researchers and fine chemical manufacturers focused on oncology drug discovery and advanced biochemical studies.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel bleomycin-based anticancer agents and targeted drug conjugates.
• Biochemical Research: Used in academic and industrial R&D to study the mechanism of action, DNA cleavage properties, and cellular uptake of bleomycin derivatives.
• Antitumor Agent Development: A critical precursor for developing next-generation chemotherapeutic compounds with modified potency and selectivity profiles.
• Conjugation Chemistry: Employed in the creation of antibody-drug conjugates (ADCs) or other targeted delivery systems due to its reactive functional groups.
• Structure-Activity Relationship (SAR) Studies: Essential for medicinal chemistry programs aiming to optimize the efficacy and reduce the toxicity of bleomycin analogues.

Basic Information

Product Name	N1-[3-[[3-[[2-(4-Chlorocyclohexyl)-1-Iminoethyl]Amino]Propyl]Methylamino]Propyl]Bleomycinamide
CAS No.	69227-45-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Bleomycinamide derivative (4-Chlorocyclohexyl); N1-(3-((3-((2-(4-Chlorocyclohexyl)-1-iminoethyl)amino)propyl)methylamino)propyl)bleomycinamide; Bleomycin A2 derivative; Modified Bleomycin; 69227-45-8; 4-Chlorocyclohexyl bleomycinamide; Bleomycin conjugate intermediate
EINECS	Contact for details

Quality Control

Our N1-[3-[[3-[[2-(4-Chlorocyclohexyl)-1-Iminoethyl]Amino]Propyl]Methylamino]Propyl]Bleomycinamide is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, MS), to ensure it meets the stringent requirements for research and development use. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.