Description

2,3,4,6-Tetrafluorobenzonitrile is a versatile fluorinated aromatic nitrile building block of significant importance in advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active ingredients, liquid crystals, and specialty polymers where the introduction of fluorine atoms is required to modulate biological activity, stability, and material properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated active pharmaceutical ingredients (APIs), including kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where fluorine substitution enhances efficacy and environmental profile.
• Liquid Crystal Materials: Serves as a precursor for fluorinated liquid crystal compounds used in high-performance displays (LCDs).
• Specialty Polymers: A monomer or modifier for engineering plastics and high-performance polymers requiring improved chemical resistance and thermal stability.
• Organic Electronics: Intermediate in the synthesis of materials for organic light-emitting diodes (OLEDs) and semiconductor layers.
• Chemical Research & Development: A valuable reagent for introducing the tetrafluorobenzonitrile moiety into novel molecular architectures in medicinal and material science chemistry.

Basic Information

Product Name	2,3,4,6-Tetrafluorobenzonitrile
CAS No.	69173-96-2
Molecular Formula	C7HF4N
Molecular Weight	175.08 g/mol
Synonyms	2,3,4,6-Tetrafluorobenzene carbonitrile; 2,3,4,6-Tetrafluorobenzonitrile; Benzonitrile, 2,3,4,6-tetrafluoro-; Tetrafluorobenzonitrile; 2,3,4,6-Tetrafluorophenyl cyanide; 69173-96-2; TFB
EINECS	Contact for details

Quality Control

Our 2,3,4,6-Tetrafluorobenzonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Related Substances (HPLC)	Total impurities ≤2.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.