Description

11Beta,17,21-Trihydroxypregna-1,4-Diene-3,20-Dione 21-Hexanoate is a synthetic corticosteroid derivative, specifically a 21-hexanoate ester of a trihydroxypregnadiene dione. This compound is valued for its role as a key pharmaceutical intermediate in the synthesis of potent anti-inflammatory and immunosuppressive steroid APIs. It is primarily required by pharmaceutical R&D and manufacturing facilities focused on developing advanced corticosteroid therapies. The product is supplied with a commitment to high purity and batch-to-batch consistency to meet stringent regulatory requirements.

Application

• Pharmaceutical Intermediate: Critical building block in the multi-step synthesis of advanced topical and systemic corticosteroids.
• Anti-inflammatory Drug Research: Used in R&D for developing new steroid-based medications targeting inflammation and autoimmune conditions.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Process Chemistry: Employed in scale-up and optimization studies for the commercial production of steroid active pharmaceutical ingredients (APIs).
• Biochemical Research: Utilized in studies investigating steroid receptor interactions and metabolic pathways.

Basic Information

Product Name	11Beta,17,21-Trihydroxypregna-1,4-Diene-3,20-Dione 21-Hexanoate
CAS No.	69164-69-8
Molecular Formula	C27H38O6
Molecular Weight	458.59 g/mol
Synonyms	Prednisolone 21-Hexanoate; 11β,17,21-Trihydroxypregna-1,4-diene-3,20-dione 21-hexanoate; Prednisolone 21-Caproate; 21-Hexanoyloxyprednisolone; NSC 106977; 11β,17α,21-Trihydroxy-1,4-pregnadiene-3,20-dione 21-hexanoate
EINECS	Contact for details

Quality Control

Our 11Beta,17,21-Trihydroxypregna-1,4-Diene-3,20-Dione 21-Hexanoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical intermediate use. Certificates of Analysis (COA) detailing all test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.