Description

(R)-1-(Isopropylamino)-3-(4-(2-Methoxyethyl)Phenoxy)Propan-2-Ol Hydrochloride is a high-purity chiral intermediate and active pharmaceutical ingredient (API) salt form. This compound is critical for ensuring the stereochemical integrity and bioavailability of advanced pharmaceutical formulations. It is primarily required by pharmaceutical R&D and manufacturing sectors for the synthesis of enantiomerically pure β-blockers and other cardiovascular agents.

Application

• Key chiral intermediate in the synthesis of enantiomerically pure β-adrenergic blocking agents (β-blockers).
• Active Pharmaceutical Ingredient (API) for advanced cardiovascular drug formulations.
• Critical building block in medicinal chemistry research for structure-activity relationship (SAR) studies.
• Reference standard for analytical method development and quality control in pharmaceutical laboratories.
• Precursor for the development of novel chiral ligands and catalysts in asymmetric synthesis.
• Used in pharmacokinetic and metabolic studies due to its defined stereochemistry.

Basic Information

Product Name	(R)-1-(Isopropylamino)-3-(4-(2-Methoxyethyl)Phenoxy)Propan-2-Ol Hydrochloride
CAS No.	68985-04-6
Molecular Formula	C15H25NO3 • HCl
Molecular Weight	303.83 g/mol (Free base: 267.36 g/mol)
Synonyms	(R)-1-(Isopropylamino)-3-[4-(2-methoxyethyl)phenoxy]propan-2-ol hydrochloride; (R)-Metoprolol Intermediate; (R)-Metoprolol Related Compound; (R)-1-[4-(2-Methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-2-propanol hydrochloride; L-1-(Isopropylamino)-3-[p-(2-methoxyethyl)phenoxy]-2-propanol hydrochloride; (R)-(-)-1-(Isopropylamino)-3-(4-(2-methoxyethyl)phenoxy)-2-propanol hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-1-(Isopropylamino)-3-(4-(2-Methoxyethyl)Phenoxy)Propan-2-Ol Hydrochloride is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity verification by HPLC, to ensure compliance with pharmaceutical-grade standards. A detailed Certificate of Analysis (COA) confirming identity, purity, and enantiomeric excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after use to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.5%
Enantiomeric Purity (Chiral HPLC)	≥99.0% (R)-isomer
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.