Description

9-Fluoro-11Beta,17,21-Trihydroxypregna-1,4-Diene-3,20-Dione 17-Butyrate is a synthetic corticosteroid derivative, specifically a fluorinated pregnadiene. This compound is of significant interest in pharmaceutical research and development due to its potent anti-inflammatory and immunosuppressive properties. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of advanced topical and systemic steroid therapies. The compound's specific structure allows for targeted activity and metabolic stability, making it a valuable intermediate for creating novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potent corticosteroid APIs (Active Pharmaceutical Ingredients).
• Anti-inflammatory Drug Research: Used in preclinical and clinical research for developing new treatments for conditions like dermatitis, psoriasis, and arthritis.
• Immunosuppressant Development: Investigated for its potential in modulating immune responses in autoimmune diseases and organ transplantation.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Biochemical Research: Used in studies to understand glucocorticoid receptor interactions and steroid metabolism pathways.
• Veterinary Medicine: Potential application in developing anti-inflammatory treatments for animals.

Basic Information

Product Name	9-Fluoro-11Beta,17,21-Trihydroxypregna-1,4-Diene-3,20-Dione 17-Butyrate
CAS No.	68791-47-9
Molecular Formula	C25H33FO6
Molecular Weight	448.53 g/mol
Synonyms	Fluprednidene 17-Butyrate; 9-Fluoro-11β,17,21-trihydroxypregna-1,4-diene-3,20-dione 17-butyrate; Fluprednylidene 17-butyrate; 17-Butyryl-9-fluoro-11β,17,21-trihydroxypregna-1,4-diene-3,20-dione; Flupredniden Butyrate; NSC 121698; SQ 15102
EINECS	Contact for details

Quality Control

Our 9-Fluoro-11Beta,17,21-Trihydroxypregna-1,4-Diene-3,20-Dione 17-Butyrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and tests for residual solvents and related substances. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP-grade requirements. Specifications can be tailored to meet specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.