Description

Afimoxifene CAS NO 68392-35-8 is a selective estrogen receptor modulator (SERM) with a well-defined pharmacological profile. This compound is of significant interest in pharmaceutical research and development, particularly for its targeted biological activity. It serves as a critical intermediate and reference standard for researchers and manufacturers in the pharmaceutical and biotechnology sectors, supporting the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of advanced therapeutic compounds targeting hormone-related pathways.
• Biochemical Research: Used as a reference standard and tool compound in studies of estrogen receptor biology and signal transduction.
• Drug Discovery & Development: Employed in preclinical research for evaluating the efficacy and mechanism of action of new SERM candidates.
• Analytical Standard: Serves as a high-purity standard for quality control and analytical method development (e.g., HPLC, LC-MS) in pharmaceutical laboratories.
• Academic Research: Utilized in university and institutional labs for fundamental research in endocrinology and cancer biology.

Basic Information

Product Name	Afimoxifene
CAS No.	68392-35-8
Molecular Formula	C25H27NO4S
Molecular Weight	437.55 g/mol
Synonyms	4-Hydroxytamoxifen; 4-OHT; (Z)-4-Hydroxytamoxifen; ICI 79280; Afimoxifene Hydrochloride; Endoxifen; Metabolite B; Metabolite Y
EINECS	Contact for details

Quality Control

Our Afimoxifene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay, related substances, and residual solvents are provided and available upon request to support your regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing under inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.