Description

Hydroxyatenolol CAS NO 68373-10-4 is a key pharmaceutical intermediate and a derivative of the β-blocker atenolol. This compound is critical for the research and development of new cardiovascular drugs and for the synthesis of related active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical manufacturers, research institutions, and fine chemical suppliers engaged in the production of advanced therapeutic agents.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of atenolol and its advanced derivatives for cardiovascular medications.
• Active Pharmaceutical Ingredient (API) Research: Serves as a reference standard and starting material in the R&D of new β-adrenergic blocking agents.
• Metabolite Studies: Used in pharmacokinetic and metabolic pathway research to understand drug behavior in biological systems.
• Analytical Standard: Employed as a high-purity standard in quality control laboratories for HPLC, LC-MS, and other analytical methods.
• Fine Chemical Synthesis: A versatile intermediate for creating specialized compounds in medicinal chemistry and custom synthesis projects.

Basic Information

Item	Details
Product Name	Hydroxyatenolol
CAS No.	68373-10-4
Molecular Formula	C14H22N2O4
Molecular Weight	282.34 g/mol
Synonyms	4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzeneacetamide; 1-(4-Carbamoylmethylphenoxy)-3-isopropylamino-2-propanol; Hydroxy Atenolol; Atenolol Hydroxy Derivative; Atenolol Impurity; Atenolol Metabolite; ATL-OH
EINECS	Contact for details

Quality Control

Our Hydroxyatenolol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via advanced techniques like HPLC and NMR. We provide Certificates of Analysis (COA) with detailed results to ensure compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.