Description

2-(2,2-Difluorobenzo[D][1,3]Dioxol-5-Yl)Acetonitrile is a specialized fluorinated organic intermediate featuring a benzodioxole core. This compound is valued for its role as a key building block in the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is essential for R&D chemists and process development scientists working on novel active ingredients that require the introduction of difluoromethylene and nitrile functional groups.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and anti-infective drugs.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and insecticides, where the difluorobenzodioxole moiety can enhance biological activity and environmental stability.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers and advanced organic electronic materials.
• Ligand and Catalyst Development: Employed in organometallic chemistry for creating novel ligands that can modulate catalytic activity in asymmetric synthesis.
• Fluorine Chemistry Studies: A valuable substrate for investigating new fluorination methodologies and the properties of fluorinated aromatic systems.

Basic Information

Product Name	2-(2,2-Difluorobenzo[D][1,3]Dioxol-5-Yl)Acetonitrile
CAS No.	68119-31-3
Molecular Formula	C9H5F2NO2
Molecular Weight	197.14 g/mol
Synonyms	5-(Cyanomethyl)-2,2-difluoro-1,3-benzodioxole; 2,2-Difluoro-1,3-benzodioxole-5-acetonitrile; 2-(2,2-Difluoro-1,3-benzodioxol-5-yl)acetonitrile; 2,2-Difluorobenzo[1,3]dioxole-5-acetonitrile; (2,2-Difluorobenzo[d][1,3]dioxol-5-yl)acetonitrile; 68119-31-3; 2,2-Difluoro-5-(cyanomethyl)-1,3-benzodioxole
EINECS	Contact for details

Quality Control

Our 2-(2,2-Difluorobenzo[D][1,3]Dioxol-5-Yl)Acetonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed specifications for trace impurities, residual solvents, and assay results. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed when not in use to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.