Description

3,4,5-Trifluoropyridine is a high-purity fluorinated heterocyclic building block of significant importance in advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and specialty materials industries.

Application

• Pharmaceutical Intermediate: A key synthon for the construction of complex drug molecules, particularly in the development of kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the trifluoromethylpyridine moiety enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalysis and material science applications.
• Functional Material Research: Employed in the synthesis of liquid crystals, organic semiconductors, and other electronic materials due to its electron-withdrawing properties.
• Fluorine Chemistry Research: An essential building block for academic and industrial research exploring new fluorination methodologies and structure-activity relationships.

Basic Information

Product Name	3,4,5-Trifluoropyridine
CAS No.	67815-54-7
Molecular Formula	C5H2F3N
Molecular Weight	133.07 g/mol
Synonyms	3,4,5-Trifluoropyridine; Pyridine, 3,4,5-trifluoro-; 3,4,5-Trifluoropyridin; 2,3,4-Trifluoropyridine (isomer); TFP
EINECS	Contact for details

Quality Control

Our 3,4,5-Trifluoropyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container must be kept tightly closed to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.