Description

Bleomycin Hydrochloride is a potent glycopeptide antibiotic complex widely recognized for its antitumor and antiviral properties. Its primary commercial value lies in its critical role as an active pharmaceutical ingredient (API) in the formulation of injectable chemotherapeutic agents. This compound is essential for pharmaceutical manufacturers, research institutions, and biotechnology companies engaged in oncology drug development, life science research, and the production of specialized therapeutic formulations.

Application

• Oncological Pharmaceutical Manufacturing: Primary API for injectable chemotherapy drugs used to treat various cancers, including Hodgkin's lymphoma, testicular cancer, and squamous cell carcinomas.
• Biomedical Research: Used as a research chemical in molecular biology and oncology studies to investigate DNA cleavage mechanisms, cell cycle arrest, and apoptosis.
• Antiviral Agent Development: Serves as a key component in research for developing treatments against certain viral infections due to its DNA-binding capabilities.
• Clinical Trial Material: Supplied as a high-purity reference standard or raw material for preclinical studies and clinical trials of new cancer therapies.
• Specialty Chemical Synthesis: Used as a starting material or intermediate in the synthesis of novel bleomycin analogs and conjugate drugs.

Basic Information

Product Name	Bleomycin Hydrochloride
CAS No.	67763-87-5
Molecular Formula	C55H84N17O21S2 • HCl
Molecular Weight	~ 1480 g/mol (as hydrochloride salt)
Synonyms	Bleomycin HCl; Bleomycin Hydrochloride Salt; Blenoxane; Bleocin; NSC-125066; Bleomycin A2/B2 Hydrochloride; Bleomycin Sulfate (common misnomer); Antibiotic Bleomycin Hydrochloride
EINECS	Contact for details

Quality Control

Our Bleomycin Hydrochloride is manufactured and tested under strict quality management systems to ensure it meets the stringent requirements for pharmaceutical use. Each batch is subjected to comprehensive analytical testing, including identification, potency assay, and impurity profiling via advanced techniques like HPLC. Certificates of Analysis (COA) are provided, detailing compliance with relevant specifications. We support customers requiring material for GMP manufacturing and can supply grades aligned with pharmacopeial standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C) or as specified on the label. This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to pale yellow, amorphous powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	NLT 95.0% (on anhydrous basis)
pH (1% Solution)	4.5 - 6.0
Water Content (KF)	NMT 5.0%
Related Substances (HPLC)	Total impurities NMT 3.0% Any single impurity NMT 1.0%
Biological Potency	Conforms to reference standard

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.