Description

2-(Methylamino)-3,5,6-Trifluoro-1,4-Benzenedicarbonitrile is a specialized fluorinated aromatic compound that serves as a critical building block in advanced chemical synthesis. Its unique structure, featuring a methylamino group and multiple fluorine atoms on a benzonitrile core, makes it a valuable precursor for developing high-performance materials and active pharmaceutical ingredients. This intermediate is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in fluorinated active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms enhance biological activity and stability.
• Material Science Precursor: Serves as a building block for high-performance polymers, liquid crystals, and organic electronic materials.
• Organic Synthesis Reagent: Employed in cross-coupling reactions and as a scaffold for constructing complex heterocyclic compounds in research laboratories.
• Fluorine Chemistry Research: A valuable compound for studying structure-activity relationships and the effects of fluorination in medicinal and material chemistry.

Basic Information

Product Name	2-(Methylamino)-3,5,6-Trifluoro-1,4-Benzenedicarbonitrile
CAS No.	67205-66-7
Molecular Formula	C10H5F3N3
Molecular Weight	230.16 g/mol
Synonyms	2-Methylamino-3,5,6-trifluorobenzene-1,4-dicarbonitrile; 3,5,6-Trifluoro-2-(methylamino)terephthalonitrile; 1,4-Dicyano-2-(methylamino)-3,5,6-trifluorobenzene; 2-(Methylamino)-3,5,6-trifluoro-1,4-dicyanobenzene; TFBMA; MA-TFBDN; 67205-66-7 (CAS Index Name)
EINECS	Contact for details

Quality Control

Our production of 2-(Methylamino)-3,5,6-Trifluoro-1,4-Benzenedicarbonitrile adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to verify identity, potency, and impurity profiles. Certificates of Analysis (COA) documenting all specifications are provided with every shipment. We support cGMP and ISO 9001 standards for pharmaceutical and industrial intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids, strong bases, and oxidizing agents. The compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.