Description

10,11-Dihydro-5-[(1-Methyl-3-Pyrrolidinyl)Methyl]-5H-Dibenzo[A,D]Cyclohepten-5-Ol is a high-purity, structurally complex organic compound that serves as a critical intermediate in advanced pharmaceutical synthesis. Its value lies in enabling the production of specific active pharmaceutical ingredients (APIs) with targeted therapeutic effects. This compound is essential for research institutions and pharmaceutical manufacturers engaged in the development and scale-up of novel drug candidates, particularly within the central nervous system (CNS) and other specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of proprietary active pharmaceutical ingredients (APIs).
• Neurological Research: Used in the research and development of compounds targeting specific neurological pathways and receptors.
• Pre-clinical & Clinical Development: Serves as a critical material for producing batches of drug candidates for pre-clinical studies and clinical trials.
• Process Chemistry & Scale-up: Employed by process chemists to develop and optimize scalable, cost-effective synthetic routes for new drugs.
• Reference Standard: Can be supplied as a high-purity analytical standard for method development and quality control in API manufacturing.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	10,11-Dihydro-5-[(1-Methyl-3-Pyrrolidinyl)Methyl]-5H-Dibenzo[A,D]Cyclohepten-5-Ol
CAS No.	67195-31-7
Molecular Formula	C22H27NO
Molecular Weight	321.46 g/mol
Synonyms	5H-Dibenzo[a,d]cyclohepten-5-ol, 10,11-dihydro-5-[(1-methyl-3-pyrrolidinyl)methyl]-; 10,11-Dihydro-5-[(1-methyl-3-pyrrolidinyl)methyl]-5H-dibenzo[a,d]cyclohepten-5-ol; 5-[(1-Methyl-3-pyrrolidinyl)methyl]-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ol; (1-Methyl-3-pyrrolidinyl)methyl Dibenzo[a,d]cycloheptenol Derivative; Nortriptyline Impurity; Nortriptyline Related Compound; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 10,11-Dihydro-5-[(1-Methyl-3-Pyrrolidinyl)Methyl]-5H-Dibenzo[A,D]Cyclohepten-5-Ol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediate use. Certificates of Analysis (COA) detailing all test results are provided with each shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.