Description

2-Methyl-1-Nitro-4-(Trifluoromethyl)Benzene is a specialized aromatic nitro compound featuring a trifluoromethyl substituent, which imparts unique chemical and physical properties. This compound is valued for its role as a versatile chemical intermediate in the synthesis of more complex molecules, particularly in advanced material and pharmaceutical research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel compounds with targeted functionalities.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring a trifluoromethyl group for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the nitro and trifluoromethyl groups contribute to biological activity.
• Material Science Research: Serves as a precursor for the development of advanced organic materials, including liquid crystals, polymers, and electronic chemicals.
• Dye and Pigment Intermediate: Employed in the synthesis of specialized dyes and pigments, leveraging its aromatic nitro structure.
• Cross-Coupling Reactions: Acts as a substrate in various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to create complex biaryl structures.
• Fluorine Chemistry Studies: An important compound for research in fluorine chemistry, exploring the effects of the CF3 group on reaction pathways and product properties.

Basic Information

Product Name	2-Methyl-1-Nitro-4-(Trifluoromethyl)Benzene
CAS No.	67192-42-1
Molecular Formula	C8H6F3NO2
Molecular Weight	205.14 g/mol
Synonyms	1-Nitro-2-methyl-4-(trifluoromethyl)benzene; 2-Methyl-α,α,α-trifluoro-p-nitrotoluene; 4-(Trifluoromethyl)-2-methylnitrobenzene; 2-Methyl-4-(trifluoromethyl)nitrobenzene; 2-Methyl-4-trifluoromethylnitrobenzene; α,α,α-Trifluoro-2-methyl-4-nitrotoluene; 4-Nitro-3-methylbenzotrifluoride
EINECS	Contact for details

Quality Control

Our 2-Methyl-1-Nitro-4-(Trifluoromethyl)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and industrial synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere when appropriate for prolonged use. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.