Description

2,4-Difluoro-5-Nitrobenzonitrile is a high-purity fluorinated aromatic nitrile building block of significant importance in advanced organic synthesis. Its unique structure, featuring both electron-withdrawing nitro and nitrile groups on a difluorinated benzene ring, makes it a versatile intermediate for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including potential herbicides and pharmaceutical candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme inhibition where the fluorine atoms enhance binding and metabolic stability.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and pesticides, leveraging its difluoro-nitrobenzonitrile scaffold.
• Material Science Research: Serves as a building block for creating specialty polymers and liquid crystals, where the fluorine atoms impart desirable properties like chemical resistance and thermal stability.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Sonogashira) and nucleophilic aromatic substitution reactions to introduce functionalized aromatic systems.
• Chemical Research & Development: A valuable standard and starting material in academic and industrial labs for exploring new synthetic pathways and creating compound libraries.

Basic Information

Product Name	2,4-Difluoro-5-Nitrobenzonitrile
CAS No.	67152-20-9
Molecular Formula	C7H2F2N2O2
Molecular Weight	184.10 g/mol
Synonyms	5-Nitro-2,4-difluorobenzonitrile; 2,4-Difluoro-5-nitrobenzenecarbonitrile; Benzonitrile, 2,4-difluoro-5-nitro-; 2,4-Difluoro-5-nitro-benzonitrile; 5-Cyano-2,4-difluoronitrobenzene
EINECS	Contact for details

Quality Control

Our 2,4-Difluoro-5-Nitrobenzonitrile is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and production applications. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in a dark place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.