Description

Befunolol Hydrochloride is a selective β-adrenergic receptor antagonist (β-blocker) used in pharmaceutical research and development. This compound is critical for studying cardiovascular pharmacology and developing therapeutic agents for conditions like hypertension and glaucoma. It is primarily utilized by pharmaceutical manufacturers, contract research organizations (CROs), and academic institutions engaged in drug discovery and formulation studies.

Application

• Pharmaceutical Active Pharmaceutical Ingredient (API): Serves as the key active component in the formulation of β-blocker medications.
• Cardiovascular Research: Used in preclinical and clinical studies to investigate mechanisms of action for hypertension and angina pectoris.
• Ophthalmic Drug Development: Applied in research for developing topical solutions to manage intraocular pressure in glaucoma.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.
• Biochemical Assays: Utilized as a tool compound in receptor binding studies and other in vitro pharmacological tests.
• Formulation Science: Aids in the development of various drug delivery systems, including tablets and controlled-release formulations.

Basic Information

Product Name	Befunolol Hydrochloride
CAS No.	66717-59-7
Molecular Formula	C16H24N2O3•HCl
Molecular Weight	328.84 g/mol
Synonyms	Befunolol HCl; 2-Acetyl-7-(2-hydroxy-3-isopropylaminopropoxy)benzofuran Hydrochloride; (RS)-1-{2-Acetyl-7-[2-hydroxy-3-(isopropylamino)propoxy]benzofuran-5-yl}oxy}-3-(isopropylamino)propan-2-ol Hydrochloride; Betaclar; Bentos; Glaucol; Glaumid; Befunololum
EINECS	Contact for details

Quality Control

Our Befunolol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, assay, and impurity profile analysis by HPLC, to ensure it meets high-purity standards suitable for pharmaceutical research. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.