Description

1,3-Difluoro-5-Methoxy-2-Nitro-Benzene is a high-purity, multi-functional aromatic building block of significant commercial importance. Its unique substitution pattern makes it a valuable intermediate for synthesizing complex molecules in advanced research and development. This compound is primarily sought after by pharmaceutical and agrochemical manufacturers for the creation of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a difluorinated aromatic core.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the nitro and methoxy groups facilitate further chemical transformations.
• Material Science Research: Serves as a building block for creating specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Manufacturing: Acts as an intermediate in the production of complex, high-performance dyes and organic pigments.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic pathways and creating novel chemical entities.
• Fluorinated Compound Library: An essential component for building libraries of fluorinated compounds in drug discovery and medicinal chemistry programs.

Basic Information

Product Name	1,3-Difluoro-5-Methoxy-2-Nitro-Benzene
CAS No.	66684-62-6
Molecular Formula	C7H5F2NO3
Molecular Weight	189.12 g/mol
Synonyms	2-Nitro-1,3-difluoro-5-methoxybenzene; 1,3-Difluoro-5-methoxy-2-nitrobenzene; 5-Methoxy-2-nitro-1,3-difluorobenzene; Benzene, 1,3-difluoro-5-methoxy-2-nitro-; 2,4-Difluoro-6-methoxy-1-nitrobenzene; 2,6-Difluoro-4-methoxy-1-nitrobenzene (isomer reference); DFMNB (abbreviation)
EINECS	Contact for details

Quality Control

Our 1,3-Difluoro-5-Methoxy-2-Nitro-Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent quality suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.