Description

Ethanamine, 2-[4-(1,2-Diphenyl-1-Butenyl)Phenoxy]-N,n-Dimethyl-, Hydrochloride, (E)- (9Ci) is a high-purity, non-steroidal selective estrogen receptor modulator (SERM) compound, supplied as its stable hydrochloride salt. This compound is a critical pharmaceutical intermediate and research chemical, valued for its specific biological activity in modulating estrogen receptor pathways. It is primarily utilized by pharmaceutical manufacturers and advanced research institutions engaged in endocrinology, oncology, and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of advanced therapeutic agents targeting hormone-responsive conditions.
• Biomedical Research: Used as a reference standard and active compound in studies of estrogen receptor biology, breast cancer research, and osteoporosis.
• Drug Discovery & Development: Serves as a core scaffold for the development and optimization of new SERM candidates with improved efficacy and safety profiles.
• Academic & Institutional Research: Employed in biochemical assays and pharmacological studies to investigate receptor-ligand interactions and signaling pathways.
• Reference Material: Provides a high-purity standard for analytical method development, validation, and quality control in laboratory settings.

Basic Information

Item	Details
Product Name	Ethanamine, 2-[4-(1,2-Diphenyl-1-Butenyl)Phenoxy]-N,n-Dimethyl-, Hydrochloride, (E)- (9Ci)
CAS No.	66584-36-9
Molecular Formula	C26H30ClNO
Molecular Weight	407.98 g/mol
Synonyms	(E)-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethanamine Hydrochloride; Toremifene Impurity; (Z)-2-(p-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylethylamine Hydrochloride; FC-1157a; Toremifene Related Compound; Toremifene EP Impurity B; Estrogen Receptor Modulator Intermediate; 2-(4-((1Z)-1,2-Diphenyl-1-buten-1-yl)phenoxy)-N,N-dimethylethanamine Hydrochloride
EINECS	Contact for details

Quality Control

Our Ethanamine, 2-[4-(1,2-Diphenyl-1-Butenyl)Phenoxy]-N,n-Dimethyl-, Hydrochloride, (E)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all test results are provided and can be tailored to meet specific client or pharmacopoeial standards (e.g., USP, EP) upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.