Description

Bornaprolol is a potent and selective β-adrenergic receptor antagonist (β-blocker) with significant pharmacological activity. This compound is a critical intermediate in the synthesis of advanced active pharmaceutical ingredients (APIs) for cardiovascular therapeutics. It is essential for pharmaceutical R&D laboratories and manufacturers developing next-generation treatments for hypertension, angina, and arrhythmias. Our high-purity Bornaprolol ensures reliable performance and consistency in your synthesis processes.

Application

• Pharmaceutical Intermediate: Primary use as a key building block in the synthesis of advanced β-blocker APIs.
• Cardiovascular Drug Research: Critical for R&D programs focused on novel antihypertensive and antiarrhythmic agents.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Process Chemistry: Used in scale-up and optimization studies for the commercial manufacturing of β-adrenergic antagonists.
• Metabolite Studies: Employed in pharmacological and toxicological studies to understand drug metabolism pathways.

Basic Information

Product Name	Bornaprolol
CAS No.	66451-06-7
Molecular Formula	C18H24N2O3
Molecular Weight	316.40 g/mol
Synonyms	1-(tert-Butylamino)-3-[(5,6,7,8-tetrahydro-cis-6,7-dihydroxy-1-naphthyl)oxy]-2-propanol; (6R,7R)-1-(tert-Butylamino)-3-[(6,7-dihydroxy-5,6,7,8-tetrahydronaphthalen-1-yl)oxy]propan-2-ol; BORN; Bornaprololum; BRN 3918415
EINECS	Contact for details

Quality Control

Our Bornaprolol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.