Description

3'-Epidaunorubicin is a key anthracycline derivative and an important intermediate in the synthesis of advanced pharmaceutical compounds. Its value lies in its role as a structural analog for developing novel chemotherapeutic agents and for biochemical research into DNA intercalation and topoisomerase inhibition. This high-purity compound is essential for pharmaceutical R&D laboratories, academic research institutions, and manufacturers focused on oncology drug discovery and development.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of novel anthracycline-based chemotherapeutic agents.
• Biochemical Research: Used as a reference standard and tool compound in studies of DNA interaction mechanisms and enzyme inhibition.
• Oncology Drug Discovery: Serves as a precursor for developing new anti-cancer drugs with potentially improved efficacy or reduced side-effect profiles.
• Academic & Clinical Research: Employed in university and hospital laboratories for investigating cancer cell biology and drug resistance mechanisms.
• Analytical Standard: Used in HPLC, LC-MS, and other analytical methods for method development, validation, and quality control of related pharmaceuticals.

Basic Information

Product Name	3'-Epidaunorubicin
CAS No.	66322-65-4
Molecular Formula	C27H29NO10
Molecular Weight	527.52 g/mol
Synonyms	3'-Epi-daunorubicin; (8S,10S)-8-Acetyl-10-[(2S,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,8,11-trihydroxy-1-methoxy-9,10-dihydro-7H-tetracene-5,12-dione; 3'-epi-DNR; Daunorubicin, 3'-epi-; 3'-Epidoxorubicin impurity; Anthracycline derivative.
EINECS	Contact for details

Quality Control

Our 3'-Epidaunorubicin is manufactured under strict quality management systems to ensure high purity and batch-to-batch consistency, suitable for research and development applications. Each batch undergoes comprehensive analytical testing, including HPLC for purity determination and spectroscopic methods for structural confirmation. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) or as specified on the label or COA. This product is light-sensitive and easily oxidized; prolonged exposure to air, light, or moisture should be avoided to maintain stability.

Specification

Item	Specification
Appearance	Red to orange-red powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.