Description

Detorubicin is a synthetic anthracycline derivative, a class of compounds renowned for their potent biological activity. This high-purity compound is critical for advanced pharmaceutical research and development, particularly in the study of novel therapeutic agents. It serves as a key intermediate and reference standard for researchers and manufacturers in the oncology and life sciences sectors, where precise chemical structure and purity are paramount for reliable results.

Application

• Pharmaceutical Research & Development: As a reference standard and key intermediate in the synthesis and study of novel anthracycline-based chemotherapeutic agents.
• Oncology Drug Discovery: Used in biochemical and pharmacological studies to investigate mechanisms of action, structure-activity relationships (SAR), and potential new cancer treatments.
• Academic & Institutional Research: Employed in university and laboratory settings for fundamental research into DNA intercalation, topoisomerase inhibition, and cytotoxic compound behavior.
• Analytical Standard: Serves as a high-purity calibrant in analytical methods such as HPLC and LC-MS for quality control and method validation in pharmaceutical analysis.
• Biochemical Reagent: Utilized in *in vitro* assays to study cellular apoptosis, drug resistance mechanisms, and the efficacy of combination therapies.

Basic Information

Product Name	Detorubicin
CAS No.	66211-92-5
Molecular Formula	C₂₇H₂₉NO₁₀
Molecular Weight	527.52 g/mol
Synonyms	4-Demethoxy-7-O-(2,6-dideoxy-α-L-lyxo-hexopyranosyl)daunomycinone; 4-Demethoxy-7-O-(2,6-dideoxy-α-L-lyxo-hexopyranosyl)adriamycinone; Detorubicin hydrochloride; (1S,3S)-3-Glycoloyl-1,2,3,4,6,11-hexahydro-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1-naphthacenyl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside; NSC 335152; Antibiotic D-104
EINECS	Contact for details

Quality Control

Our Detorubicin is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research applications. Each lot undergoes comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee compliance with your specifications and research integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	Orange to red powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.