Description

Saframycin E CAS NO 66082-31-3 is a potent quinone-containing antibiotic compound belonging to the saframycin family, known for its significant biological activity. This compound is valued in advanced research for its unique mechanism of action, which involves DNA intercalation and alkylation, making it a critical tool for studying cellular processes and developing novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories, academic institutions, and biotechnology companies engaged in oncology research, antimicrobial discovery, and molecular biology studies.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the discovery of new anticancer and antimicrobial agents.
• Biochemical Studies: Used as a molecular probe to investigate DNA interaction mechanisms, apoptosis induction, and specific enzyme inhibition pathways.
• Antibiotic Mechanism Research: Employed in microbiological assays to study structure-activity relationships (SAR) within the saframycin class of antibiotics.
• Academic Research: Utilized in university and institutional labs for chemical biology projects and the synthesis of novel analogs for biological evaluation.

Basic Information

Product Name	Saframycin E
CAS No.	66082-31-3
Molecular Formula	C₂₉H₃₃N₃O₈
Molecular Weight	551.59 g/mol
Synonyms	Saframycin E; Antibiotic C-15003 P-3; NSC 339641; (1S,12S,13S,14S,26S,27S,28S)-12,13,14,26,27,28-Hexahydro-1,12-dimethyl-8,21-dinitro-7,20-bis(1-oxopropoxy)-1H,11H-[1,4,7,10,13,16,19,22]octaoxacyclotetracosin-5,18-dione; 1,12-Dimethyl-8,21-dinitro-7,20-bis(1-oxopropoxy)-12,13,14,26,27,28-hexahydro-1H,11H-[1,4,7,10,13,16,19,22]octaoxacyclotetracosin-5,18-dione
EINECS	Contact for details

Quality Control

Our Saframycin E is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity determination and spectroscopic methods for structural confirmation. A Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, cool place. For long-term storage, consider keeping the product at 2-8°C under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.