Description

Saframycin C CAS NO 66082-29-9 is a potent quinone-containing antibiotic belonging to the saframycin family, characterized by its unique pentacyclic structure. This compound is valued for its significant biological activity, particularly as a DNA-binding agent and topoisomerase inhibitor, making it a crucial entity in biochemical research and development. It is primarily sought by pharmaceutical R&D laboratories, academic institutions, and biotechnology companies engaged in oncology research, antimicrobial discovery, and the study of novel therapeutic mechanisms.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the development of novel anti-cancer and antimicrobial agents.
• Biochemical Studies: Used as a molecular probe to investigate DNA interaction mechanisms, topoisomerase inhibition, and apoptosis induction in cellular models.
• Antimicrobial Agent Development: Explored for its potent activity against Gram-positive bacteria and its potential in addressing antibiotic-resistant strains.
• Academic Research: Utilized in university and institutional labs for studying the structure-activity relationships (SAR) of quinone antibiotics and their biosynthesis pathways.
• Preclinical Studies: Employed in in vitro and in vivo models to evaluate efficacy, pharmacokinetics, and toxicology profiles for potential drug candidates.

Basic Information

Product Name	Saframycin C
CAS No.	66082-29-9
Molecular Formula	C₂₈H₃₀N₄O₇
Molecular Weight	534.56 g/mol
Synonyms	Saframycin C; Antibiotic C 15003; NSC 339638; (3S,4aS,13aS,14R)-14-[(2S)-2-Aminopropanamido]-10-ethyl-3,4,4a,5,13,13a,14,15-octah-2,7,12-triazapentacene-6,11,16-trione; 1,2,3,4,6,11,12,13-Octahydro-2,7,12-triazapentacene-6,11,16-trione derivative
EINECS	Contact for details

Quality Control

Our Saframycin C is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity determination, spectroscopic identification (IR, NMR, MS), and residual solvent analysis to ensure it meets high-purity standards suitable for research applications. A Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment to guarantee traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and handled under appropriate conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	Orange to red-brown powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.