Description

Bometolol Hydrochloride is a high-purity pharmaceutical intermediate and active pharmaceutical ingredient (API) with the CAS registry number 65023-16-7. This compound is critical for research and development in the cardiovascular therapeutic area, serving as a key building block for advanced β-blocker formulations. It is primarily utilized by pharmaceutical manufacturers, contract research organizations (CROs), and academic research institutions focused on developing new antihypertensive and antiarrhythmic agents.

Application

• Pharmaceutical API Synthesis: Primary use as an active pharmaceutical ingredient in the manufacture of β-adrenergic blocking agents (β-blockers).
• Cardiovascular Drug Development: A crucial intermediate in R&D for novel antihypertensive and antianginal medications.
• Clinical Research Materials: Sourced for preclinical and clinical trial material preparation under GMP guidelines.
• Reference Standard: Used as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.
• Biochemical Research: Employed in studies investigating β-adrenergic receptor mechanisms and signal transduction pathways.

Basic Information

Product Name	Bometolol Hydrochloride
CAS No.	65023-16-7
Molecular Formula	C16H25N3O3 • HCl
Molecular Weight	351.85 g/mol (Hydrochloride salt)
Synonyms	Bometolol HCl; 1-(tert-Butylamino)-3-[(5,6,7,8-tetrahydro-1,6-naphthyridin-6-yl)oxy]-2-propanol Hydrochloride; Bometolol Monohydrochloride; (RS)-Bometolol Hydrochloride; (±)-Bometolol Hydrochloride; Bometolol Hydrochloride (USAN); Bometolol HCL
EINECS	Contact for details

Quality Control

Our Bometolol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via HPLC, to ensure it meets stringent specifications for pharmaceutical use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment, supporting compliance with cGMP and ICH Q7 guidelines for active pharmaceutical ingredients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect stability and potency. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.