Description

2-Methyl-1-[4-(Trifluoromethyl)Phenyl]Propan-1-One is a specialized aromatic ketone featuring a trifluoromethyl substituent, a structural motif of significant interest in advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of pharmaceuticals and agrochemicals, where the CF3 group is known to enhance metabolic stability and lipophilicity. It is primarily sought by research and development chemists, process development teams, and manufacturers in the fine chemical and life science industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group improves biological activity and environmental persistence.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated organic compounds used in electronic displays and optoelectronic devices.
• Organic Synthesis & Catalysis Research: Employed in academic and industrial R&D for studying novel reaction pathways, asymmetric synthesis, and as a ligand precursor in catalysis.
• Advanced Polymer Chemistry: Acts as a monomer or modifier in the development of specialty polymers with enhanced chemical resistance and thermal stability.

Basic Information

Product Name	2-Methyl-1-[4-(Trifluoromethyl)Phenyl]Propan-1-One
CAS No.	64436-58-4
Molecular Formula	C11H11F3O
Molecular Weight	216.20 g/mol
Synonyms	1-[4-(Trifluoromethyl)phenyl]-2-methylpropan-1-one; 2-Methyl-1-(4-trifluoromethylphenyl)propan-1-one; 4'-Trifluoromethylisobutyrophenone; α,α-Dimethyl-4-(trifluoromethyl)benzeneacetone; p-Trifluoromethylisobutyrophenone; 4-(Trifluoromethyl)isobutyrophenone; Benzeneacetone, α,α-dimethyl-4-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our production of 2-Methyl-1-[4-(Trifluoromethyl)Phenyl]Propan-1-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is characterized and controlled using advanced analytical techniques including GC, HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment, supporting compliance with cGMP and ISO 9001 standards for research and commercial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and potential contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.