Description

Aclacinomycin S is a potent anthracycline antibiotic compound, identified by CAS NO 64431-69-2. This molecule is valued for its significant biological activity, particularly as a key intermediate or reference standard in advanced pharmaceutical research and development. It is primarily utilized by research institutions, pharmaceutical companies, and biotechnology firms engaged in the discovery and synthesis of novel anticancer agents and antibiotics.

Application

• Pharmaceutical Research & Development: Serves as a critical reference standard and building block in the synthesis and study of novel anthracycline-based chemotherapeutic agents.
• Anticancer Agent Studies: Used in biochemical and pharmacological research to investigate mechanisms of action, such as topoisomerase II inhibition and DNA intercalation.
• Antibiotic Research: Employed as a model compound in microbiological studies to explore structure-activity relationships (SAR) against various bacterial strains.
• Biochemical Assay Standard: Acts as a high-purity calibrant or control in analytical methods like HPLC and LC-MS for quality control in related API manufacturing.
• Academic Research: Utilized in university and institutional labs for fundamental studies in medicinal chemistry and molecular biology.

Basic Information

Product Name	Aclacinomycin S
CAS No.	64431-69-2
Molecular Formula	C₄₂H₅₃NO₁₅
Molecular Weight	811.87 g/mol
Synonyms	Aclacinomycin S; Aclarubicin S; Antibiotic MA 144 S; 2-Ethyl-1,2,3,4,6,11-hexahydro-2,5,7-trihydroxy-6,11-dioxo-4-[[2,3,6-trideoxy-4-O-[2,6-dideoxy-4-O-[(2R,6S)-tetrahydro-6-methyl-5-oxo-2H-pyran-2-yl]-α-L-lyxo-hexopyranosyl]-3-(dimethylamino)-α-L-lyxo-hexopyranosyl]oxy]-1-naphthacenecarboxylic acid methyl ester; MA 144 S
EINECS	Contact for details

Quality Control

Our Aclacinomycin S is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed in a desiccated environment and handled under appropriate conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.