Description

Medorubicin is a potent anthracycline derivative and an important pharmaceutical intermediate. This compound is critical for the research and development of novel chemotherapeutic agents, particularly in the study of anticancer drug mechanisms and structure-activity relationships. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of active pharmaceutical ingredients (APIs) focused on oncology.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of advanced anthracycline-based chemotherapeutic agents.
• Oncology Research: Used as a reference standard and experimental compound in biochemical and pharmacological studies targeting cancer cells.
• Mechanism of Action Studies: Investigated for its interaction with topoisomerase II and DNA intercalation properties.
• Structure-Activity Relationship (SAR) Analysis: Serves as a core structure for modifying and developing new analogs with improved efficacy or reduced side effects.
• Academic and Clinical Research: Employed in university and hospital laboratories for preclinical cancer research.
• API Development: Integral component in the development and scale-up processes for novel anticancer drug candidates.

Basic Information

Product Name	Medorubicin
CAS No.	64314-52-9
Molecular Formula	C₂₆H₂₉NO₁₀
Molecular Weight	515.51 g/mol
Synonyms	4'-Epidoxorubicin; 4'-Epidoxorubicin Hydrochloride; 4'-Epidoxorubicinol; 4'-Epidoxorubicinol Hydrochloride; 4'-Epidoxorubicinol HCl; 4'-Epidoxorubicinol Hydrochloride Salt; (8S,10S)-10-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-glycoloyl-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione
EINECS	Contact for details

Quality Control

Our Medorubicin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by spectroscopic methods, and stringent control of related substances and residual solvents. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to ensure traceability and compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is strictly light-sensitive and hygroscopic (moisture-sensitive). For long-term storage, consider desiccated conditions under an inert atmosphere.

Specification

Item	Specification
Appearance	Orange-red to red powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.