Description

3,5-Difluorobenzonitrile is a versatile fluorinated aromatic nitrile building block essential for advanced organic synthesis. Its unique structure, featuring two fluorine atoms in a meta-substitution pattern, makes it a critical intermediate for introducing the difluorobenzene moiety into complex molecules. This compound is primarily sought after by R&D and production chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients. Its high purity and consistent quality are paramount for ensuring reliable downstream reactions and final product efficacy.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors, anti-cancer agents, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the difluorophenyl group enhances biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for high-performance displays (LCDs).
• Polymer Chemistry: Acts as a monomer or modifier in the synthesis of specialty polymers, including high-temperature resins and materials with specific dielectric properties.
• Organic Electronics: Utilized in the research and development of organic light-emitting diodes (OLEDs) and semiconductor materials.
• Chemical Research & Development: A valuable reagent for exploring new reaction pathways and creating novel fluorinated compounds in academic and industrial labs.

Basic Information

Product Name	3,5-Difluorobenzonitrile
CAS No.	64248-63-1
Molecular Formula	C7H3F2N
Molecular Weight	139.10 g/mol
Synonyms	3,5-Difluorobenzonitrile; 3,5-Difluorophenyl cyanide; Benzonitrile, 3,5-difluoro-; 3,5-Difluorobenzene carbonitrile; 3,5-Difluorobenzonitrile (DFBN); 3,5-Difluorobenzyl nitrile; 3,5-Difluorophenylcarbonitrile; 64248-63-1
EINECS	Contact for details

Quality Control

Our 3,5-Difluorobenzonitrile is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality parameters. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	48 - 52 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.