Description

1-(4-Fluorophenyl)-1,3-Dihydro Isobenzofuran-5-Carbonitile is a high-purity organic intermediate characterized by its unique fused isobenzofuran structure with a fluorophenyl substituent and a nitrile functional group. This compound is a critical building block in advanced organic synthesis, offering a versatile scaffold for constructing complex molecules. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing specific receptor-binding activities.
• Agrochemical Research: Serves as a core structure for developing new herbicides, fungicides, or insecticides, leveraging the bioactivity of the fluorinated aromatic system.
• Material Science: Used in the research and development of specialty polymers, liquid crystals, or organic electronic materials due to its rigid, planar structure.
• Chemical Synthesis: Acts as a versatile synthon in organic chemistry for constructing complex heterocyclic compounds and fluorinated aromatic systems.
• Academic & Industrial R&D: Employed in research laboratories for methodological studies, catalysis development, and exploring new chemical spaces.

Basic Information

Product Name	1-(4-Fluorophenyl)-1,3-Dihydro Isobenzofuran-5-Carbonitile
CAS No.	64169-67-1
Molecular Formula	C15H10FNO
Molecular Weight	239.25 g/mol
Synonyms	5-Cyano-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran; 1-(4-Fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile; 1-(p-Fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile; 5-Cyano-1-(p-fluorophenyl)-1,3-dihydro-2-benzofuran; 2-Benzofurancarbonitrile, 1,3-dihydro-1-(4-fluorophenyl)-; 64169-67-1; 1-(4-Fluorophenyl)-5-cyano-1,3-dihydroisobenzofuran
EINECS	Contact for details

Quality Control

Our production of 1-(4-Fluorophenyl)-1,3-Dihydro Isobenzofuran-5-Carbonitile adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Our quality system is designed to support cGMP requirements for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 1.0%; Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.