Description

9-Fluoropregna-1,4-Diene-11,17,21-Triol-3,20-Dione17,21-Diacetate is a high-purity fluorinated steroid derivative, a key intermediate in advanced pharmaceutical synthesis. Its value lies in its precise molecular structure, which is critical for developing potent corticosteroid analogs with targeted therapeutic effects. This compound is essential for R&D and production teams in the pharmaceutical industry, particularly those focused on anti-inflammatory, immunosuppressive, and dermatological drug development.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of advanced corticosteroid drugs, including potent topical and systemic formulations.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in the research and scale-up manufacturing of novel steroid-based APIs.
• Biochemical Research: Used in laboratory studies to investigate steroid receptor interactions, metabolic pathways, and structure-activity relationships (SAR).
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in pharmaceutical testing laboratories.
• Process Chemistry: Utilized in optimizing synthetic routes for the efficient and cost-effective production of fluorinated steroid compounds.

Basic Information

Product Name	9-Fluoropregna-1,4-Diene-11,17,21-Triol-3,20-Dione17,21-Diacetate
CAS No.	64088-99-9
Molecular Formula	C₂₅H₃₁FO₇
Molecular Weight	462.51 g/mol
Synonyms	9-Fluoro-11β,17,21-trihydroxypregna-1,4-diene-3,20-dione 17,21-diacetate; 9α-Fluoroprednisolone 17,21-diacetate; 9-Fluoroprednisolone 17,21-diacetate; NSC 47439; Fluprednisolone 17,21-diacetate; 9α-Fluoro-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione 17,21-diacetate
EINECS	Contact for details

Quality Control

Our 9-Fluoropregna-1,4-Diene-11,17,21-Triol-3,20-Dione17,21-Diacetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis, to ensure it meets the stringent requirements for pharmaceutical intermediates. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.