Description

Esorubicin is a synthetic anthracycline derivative and a key intermediate in pharmaceutical research and development. This compound is valued for its role in the synthesis and study of novel chemotherapeutic agents, offering researchers a critical building block for drug discovery programs. It is primarily utilized by pharmaceutical R&D laboratories, academic institutions, and fine chemical manufacturers focused on oncology and antibiotic research.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of advanced anthracycline-based chemotherapeutic agents.
• Biochemical Research: Used in studies investigating the structure-activity relationships (SAR) of anthracycline antibiotics to develop compounds with improved efficacy and reduced side effects.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis (HPLC, LC-MS).
• Mechanistic Studies: Employed in preclinical research to explore mechanisms of action, including DNA intercalation and topoisomerase II inhibition.
• Academic Research: Utilized in university and institutional labs for chemical synthesis projects and medicinal chemistry coursework.

Basic Information

Product Name	Esorubicin
CAS No.	63521-85-7
Molecular Formula	C25H27NO10
Molecular Weight	501.48 g/mol
Synonyms	4'-Deoxy-4'-iododoxorubicin; 4'-Iodo-4'-deoxydoxorubicin; Iodoxorubicin; NSC-321467; (8S,10S)-10-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-glycoloyl-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione
EINECS	Contact for details

Quality Control

Our Esorubicin is manufactured under strict quality management systems to ensure high purity and batch-to-batch consistency, suitable for research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	Orange to red powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.