Description

1β-Hydroxy Vitamin D3 is a key intermediate in the synthesis of active vitamin D metabolites and analogs. This compound is of significant commercial and research interest due to its role as a precursor in the production of pharmaceuticals targeting calcium regulation and bone health. It is primarily utilized by manufacturers in the pharmaceutical, nutraceutical, and fine chemical industries for the development of advanced therapeutic agents.

Application

• Pharmaceutical Intermediate: Critical precursor for the synthesis of active vitamin D analogs like calcitriol and its derivatives.
• Research & Development: Used in biochemical and pharmacological studies to investigate vitamin D metabolism and receptor interactions.
• Nutraceutical Ingredient Synthesis: Employed in the controlled production of high-potency vitamin D supplements.
• Fine Chemical Synthesis: Serves as a building block for creating novel steroidal compounds with targeted biological activity.
• Reference Standard: Used as a certified reference material (CRM) in analytical laboratories for quality control and method validation.

Basic Information

Product Name	1β-Hydroxy Vitamin D3
CAS No.	63181-13-5
Molecular Formula	C₂₇H₄₄O₂
Molecular Weight	400.64 g/mol
Synonyms	1α-Hydroxy Vitamin D3 (common misnomer); 1β-Hydroxycholecalciferol; 1β-OH-D3; (5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-1β,3β-diol; 1β-Hydroxycolecalciferol; Precursor of 1,25-Dihydroxyvitamin D3
EINECS	Contact for details

Quality Control

Our 1β-Hydroxy Vitamin D3 is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets high-purity standards suitable for pharmaceutical R&D and synthesis. Certificates of Analysis (COA) documenting full specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.