Description

Tetraethylammonium Fluoride Trihydrate is a versatile, hygroscopic quaternary ammonium salt that serves as a powerful source of "naked" fluoride ions. This compound is critical for facilitating challenging nucleophilic fluorination and desilylation reactions in organic synthesis. It is an essential reagent for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, enabling the precise introduction of fluorine atoms to modulate the properties of target molecules.

Application

• Nucleophilic Fluorination: A key reagent for the synthesis of fluorinated organic compounds, including aryl fluorides and fluorinated heterocycles, which are prevalent in modern pharmaceuticals and agrochemicals.
• Desilylation Agent: Efficiently removes silyl protecting groups (e.g., TMS, TBDMS, TIPS) in complex multi-step synthetic sequences, particularly in fine chemical and peptide synthesis.
• Phase-Transfer Catalyst (PTC): Acts as a catalyst in two-phase reaction systems to enhance the reactivity of fluoride ions in organic media.
• Electrolyte Additive: Used in research and development of advanced battery systems, including lithium-ion and fluoride-ion batteries, to improve ionic conductivity and electrode stability.
• Polymer Chemistry: Employed as an initiator or catalyst in the polymerization of specific monomers and in the surface modification of polymers.
• Material Science Research: Utilized in the preparation of fluoride-containing ceramics, glasses, and other advanced inorganic materials.

Basic Information

Product Name	Tetraethylammonium Fluoride Trihydrate
CAS No.	63123-00-2
Molecular Formula	C8H20FNO3 or (C2H5)4N·F·3H2O
Molecular Weight	197.25 g/mol (anhydrous basis)
Synonyms	TEA Fluoride Trihydrate; Tetraethylammonium Fluoride 3-Hydrate; N,N,N-Triethylethanaminium Fluoride Trihydrate; TEF; Et4NF·3H2O; Fluorotetraethylammonium Trihydrate; Tetraethylammonium Fluoride Hydrate
EINECS	Contact for details

Quality Control

Our Tetraethylammonium Fluoride Trihydrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing assay, impurity profile, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic nature, this product must be stored in a cool, dry place, ideally under an inert atmosphere such as nitrogen or argon to prevent moisture absorption and decomposition. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms
Assay (Titration)	≥ 98.0% (on anhydrous basis)
Water Content (KF)	20.0% - 25.0% (Theoretical: ~21.4%)
Heavy Metals (as Pb)	≤ 10 ppm
Chloride (Cl)	≤ 0.1%
Sulfate (SO4)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.