Description

Bopindolol Malonate CAS NO 62658-64-4 is a high-purity chemical intermediate of significant importance in advanced pharmaceutical synthesis. This compound serves as a key building block in the research and development of β-adrenergic blocking agents, offering precise structural control for creating novel therapeutic molecules. It is primarily required by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in cardiovascular drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of Bopindolol and related β-blocker (β-adrenergic antagonist) active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new cardiovascular drug candidates.
• Process Chemistry: Employed in route scouting, optimization, and scale-up activities for the commercial manufacturing of specialty pharmaceuticals.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development, validation, and quality control testing in pharmaceutical analysis.
• Biochemical Research: Utilized in pharmacological studies to investigate β-adrenergic receptor interactions and mechanisms of action.

Basic Information

Product Name	Bopindolol Malonate
CAS No.	62658-64-4
Molecular Formula	C23H28N2O4
Molecular Weight	396.48 g/mol
Synonyms	1-(tert-Butylamino)-3-[(2-methyl-1H-indol-4-yl)oxy]-2-propanol Malonate; 4-[2-(tert-Butylamino)-1-hydroxyethyl]-2-methyl-1H-indole Malonate; Bopindolol Hydrogen Malonate; (RS)-1-(tert-Butylamino)-3-[(2-methylindol-4-yl)oxy]propan-2-ol Malonate; Bopindolol (base) Malonate Salt; LM 210; Contact for other trade names.
EINECS	Contact for details

Quality Control

Our Bopindolol Malonate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis to ensure it meets stringent specifications for pharmaceutical R&D use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability, consistency, and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.