Description

2-Chloro-3-(Trifluoromethyl)Benzonitrile is a versatile halogenated aromatic nitrile building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both chloro and trifluoromethyl substituents, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by R&D chemists and process development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used to construct advanced herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the trifluoromethyl group.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, such as semiconductors and liquid crystals, due to its electron-withdrawing character.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom chemical synthesis services catering to specialized R&D projects.

Basic Information

Product Name	2-Chloro-3-(Trifluoromethyl)Benzonitrile
CAS No.	62584-32-1
Molecular Formula	C8H3ClF3N
Molecular Weight	205.56 g/mol
Synonyms	2-Chloro-α,α,α-trifluoro-m-tolunitrile; 2-Chloro-3-(trifluoromethyl)benzenecarbonitrile; 3-Cyano-2-chlorobenzotrifluoride; 2-Chloro-3-trifluoromethylbenzonitrile; m-(Trifluoromethyl)-o-chlorobenzonitrile; 2-Chloro-α,α,α-trifluoro-3-methylbenzonitrile; 62584-32-1; 2-Chloro-3-trifluoromethyl phenyl cyanide
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-3-(Trifluoromethyl)Benzonitrile is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by GC, HPLC, and NMR.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.