Description

3,5-Bis(Trifluoromethyl)-4-Chlorobenzonitrile is a high-value, multi-functional aromatic intermediate characterized by its unique trifluoromethyl and cyano substituents. This compound is essential for introducing lipophilicity, metabolic stability, and electron-withdrawing properties into advanced molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for synthesizing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in oncology, antiviral, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl groups enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of monomers for specialty polymers, liquid crystals, and organic electronic materials.
• Custom Synthesis & Contract Manufacturing: A critical starting material for fine chemical manufacturers offering bespoke synthesis services.

Basic Information

Product Name	3,5-Bis(Trifluoromethyl)-4-Chlorobenzonitrile
CAS No.	62584-30-9
Molecular Formula	C9H2ClF6N
Molecular Weight	273.56 g/mol
Synonyms	4-Chloro-3,5-bis(trifluoromethyl)benzonitrile; 3,5-Bis(trifluoromethyl)-4-chlorobenzene carbonitrile; 4-Chloro-α,α,α,α',α',α'-hexafluoro-3,5-xylyl cyanide; 4-Chloro-3,5-di(trifluoromethyl)benzonitrile; Benzonitrile, 4-chloro-3,5-bis(trifluoromethyl)-; 3,5-Di(trifluoromethyl)-4-chlorobenzonitrile
EINECS	Contact for details

Quality Control

Our 3,5-Bis(Trifluoromethyl)-4-Chlorobenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.