Description

5,12-Naphthacenedione, 10-((3-Amino-2,3-Dideoxy-α-L-Ribo-Hexopyran Osyl)Oxy)-7,8,9,10-Tetrahydro-6,8,11-Trihydroxy-8-(Hydroxyacetyl)-1-Me Thoxy-, (8S-Cis)- is a complex, high-purity anthracycline derivative of significant interest in advanced pharmaceutical research and development. This compound matters as a key synthetic intermediate or reference standard for the development of novel chemotherapeutic agents and antibiotics, offering researchers a critical building block with defined stereochemistry. It is primarily needed by R&D laboratories, pharmaceutical manufacturers, and academic institutions focused on oncology, infectious disease, and medicinal chemistry.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel anthracycline-based chemotherapeutic drugs.
• Reference Standard: Used for analytical method development, validation, and quality control (QC/QA) in pharmaceutical manufacturing.
• Biochemical Research: Employed in studies investigating DNA intercalation mechanisms, topoisomerase inhibition, and antibiotic action.
• Medicinal Chemistry: A valuable scaffold for structure-activity relationship (SAR) studies to develop new anticancer and antimicrobial agents.
• Academic & Institutional R&D: Utilized in university and research institute laboratories for exploratory life science projects.

Basic Information

Product Name	5,12-Naphthacenedione, 10-((3-Amino-2,3-Dideoxy-α-L-Ribo-Hexopyran Osyl)Oxy)-7,8,9,10-Tetrahydro-6,8,11-Trihydroxy-8-(Hydroxyacetyl)-1-Me Thoxy-, (8S-Cis)-
CAS No.	62414-01-1
Molecular Formula	C27H31NO13
Molecular Weight	577.54 g/mol
Synonyms	10-((3-Amino-2,3-dideoxy-α-L-ribo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione; (8S-cis)-Daunorubicin derivative; 4-Demethoxy-7,9-O-methylene-13-deoxo-13-oxodaunorubicin; Anthracycline glycoside intermediate; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 5,12-Naphthacenedione derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS), to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed immediately after use to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	Orange to red powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.