Description

20-Dihydroprednisolonic Acid CAS NO 62358-12-7 is a key steroid derivative and synthetic intermediate of significant importance in advanced pharmaceutical manufacturing. Its primary value lies in its role as a crucial precursor for the synthesis of potent anti-inflammatory corticosteroids, including prednisolone and related analogs. This high-purity intermediate is essential for research and production facilities in the pharmaceutical and fine chemical sectors, where precise chemical building blocks are required for developing active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of corticosteroid drugs such as prednisolone and methylprednisolone.
• Anti-inflammatory API Synthesis: Used in the research and commercial production of active pharmaceutical ingredients (APIs) for treating inflammatory and autoimmune conditions.
• Steroid Chemistry Research: Serves as a valuable reference standard and starting material in academic and industrial steroid research programs.
• Fine Chemical Manufacturing: Employed in the production of specialized steroid derivatives for various therapeutic applications.
• Process Development: Utilized in the development and optimization of synthetic routes for steroid-based pharmaceuticals.

Basic Information

Product Name	20-Dihydroprednisolonic Acid
CAS No.	62358-12-7
Molecular Formula	C21H28O5
Molecular Weight	360.45 g/mol
Synonyms	20-Dihydro-11-deoxy-21-hydroxypregn-4-ene-3,20-dione-17α-carboxylic acid; 17α-Carboxy-20-dihydro-11-deoxy-21-hydroxypregn-4-ene-3,20-dione; 20-Dihydro-11-deoxycortisone-17α-carboxylic acid; Prednisolonic Acid derivative; 20-Dihydro-17α-carboxyprednisolone; 20-DHP Acid; 62358-12-7; 20-Dihydroprednisolone-17α-carboxylic acid
EINECS	Contact for details

Quality Control

Our 20-Dihydroprednisolonic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical synthesis. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, to meet stringent internal specifications. A Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with every shipment. We adhere to cGMP principles where applicable to support our customers' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.