Description

Dehydrocarteolol Hydrochloride is a high-purity pharmaceutical intermediate and reference standard of significant importance in medicinal chemistry research and development. Its primary value lies in its role as a key derivative of carteolol, a non-selective β-adrenergic blocking agent, enabling advanced pharmacological studies and analytical method development. This compound is essential for researchers and manufacturers in the pharmaceutical industry focusing on cardiovascular drug development, metabolite identification, and impurity profiling.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis and research of β-blocker drugs and their related analogs.
• Reference Standard: Used for analytical method validation, quality control (QC), and quality assurance (QA) in pharmaceutical manufacturing to ensure product purity and consistency.
• Metabolite Studies: Employed in pharmacokinetic and metabolic pathway research to understand the biotransformation of carteolol.
• Impurity Profiling: Serves as a known impurity or degradation product standard for stability testing and regulatory filing of carteolol-based pharmaceuticals.
• Biochemical Research: Utilized in vitro studies to investigate the structure-activity relationships (SAR) of β-adrenergic receptor antagonists.
• Academic Research: A valuable compound for universities and research institutions conducting studies in medicinal chemistry, pharmacology, and organic synthesis.

Basic Information

Product Name	Dehydrocarteolol Hydrochloride
CAS No.	62330-84-1
Molecular Formula	C16H24N2O3·HCl
Molecular Weight	328.84 g/mol
Synonyms	5-[3-[(1,1-Dimethylethyl)amino]-2-hydroxypropoxy]-3,4-dihydro-2(1H)-quinolinone Hydrochloride; 8-[3-(tert-Butylamino)-2-hydroxypropoxy]-5,6,7,8-tetrahydrocarbostyril Hydrochloride; Dehydrocarteolol HCl; (RS)-5-[3-(tert-Butylamino)-2-hydroxypropoxy]-3,4-dihydrocarbostyril Hydrochloride; Carteolol Impurity C (Hydrochloride); Carteolol Related Compound C
EINECS	Contact for details

Quality Control

Our Dehydrocarteolol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis, to ensure it meets stringent specifications for pharmaceutical research. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.