Description

n-Octanoyldaunorubicin is a semi-synthetic anthracycline derivative, specifically an esterified analog of the potent anticancer agent daunorubicin. This compound is primarily valued as a key pharmaceutical intermediate in the research and development of novel chemotherapeutic agents, offering a modified structure for exploring enhanced efficacy and reduced toxicity profiles. It is essential for academic researchers, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on oncology drug discovery and advanced synthesis.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel anthracycline-based anticancer drugs and prodrugs.
• Oncology Research: Used in biochemical and pharmacological studies to investigate structure-activity relationships (SAR) and mechanisms of action against various cancer cell lines.
• Medicinal Chemistry: Serves as a precursor for the development of derivatives with potentially improved therapeutic indices, targeting reduced cardiotoxicity.
• Reference Standard: Employed as a high-purity analytical standard in quality control (QC) and method development for related pharmaceutical products.
• Bioconjugation Studies: Utilized in research exploring antibody-drug conjugates (ADCs) or other targeted delivery systems for chemotherapy.

Basic Information

Product Name	n-Octanoyldaunorubicin
CAS No.	62327-70-2
Molecular Formula	C35H41NO12
Molecular Weight	667.70 g/mol
Synonyms	8-O-Octanoyldaunorubicin; Daunorubicin 8-octanoate; Octanoyl daunorubicin; 4-Demethoxy-7-O-[3,5-dideoxy-4-O-octanoyl-α-L-lyxo-heptapyranosyl]adriamycinone; AD 143; NSC 354646; 4-Demethoxydaunorubicin 8-octanoate
EINECS	Contact for details

Quality Control

Our n-Octanoyldaunorubicin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for research and pharmaceutical intermediate applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the certificate of analysis. Keep the container in a dry, cool, and well-ventilated area. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Orange to red powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.